5848vip威尼斯电子游戏彭长庚老师课题组(分子神经科学实验室)近年来解析了miR-183家簇在神经病理性疼痛中的功能和分子机制【1-3】,课题组介绍见https://mednew.tongji.edu.cn/ktz/Group.aspx?id=46。因课题需要,招聘1名博士后,分析miRNA敲除小鼠(已繁殖且有表型)的疼痛和其它表型、解析表型的分子机制。课题组现有成员团结友爱、学术氛围浓。希望有志于从事神经科学的、有自我驱动力、执行力和创造力的优秀青年才俊应聘,有动物实验、分子遗传和测序数据分析经验的优先考虑。请发送简历(含照片)至changgeng.peng@tongji.edu.cn,截止日期2021年10月30号。应聘材料会保密,但恕不退回。
1. Sun L, Xia R, Jiang J, Wen T, Huang Z, Qian R, Zhang M, Zhou M, Peng C. MicroRNA-96 is required to prevent allodynia by repressing voltage-gated sodium channels in spinal cord. Progress in Neurobiology,2021. Feb 23;102024.
2. Peng C§,Furlan A, Zhang M, Su J, Lübke M, Lönnerberg P, Abdo H, Sontheimer J, Sundström E, Ernfors P2§. Termination of cell-type specification gene programs by miR-183 cluster determines the population sizes of low threshold mechanosensitive neurons. Development. 2018 Sep 25;145(18):dev165613. (§共同通讯作者).
3. Peng C, Li L, Zhang M, Gonzales C, Parisien M, Belfer I, Usoskin D, Abdo H, Furlan A, Häring M, Lallemend F, Harkany T, Diatchenko L, Hökfelt T, Hjerling-Leffler J and Ernfors P. MiR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes. Science. 2017 Jun 16;356(6343):1168-1171. (Science同期杂志上发表了Perspective review).