临床工作业绩（Clinical performance）
从事内科工作20余年，熟练掌握内科学急、危、重症的诊治，尤其擅长急性心力衰竭、急性心肌梗死、高血压危象、主动脉夹层、恶性心律失常等的诊治，熟练掌握心内科常见病的诊治，包括高血压病、冠心病、心律失常、心肌病、心包炎、心肌炎、瓣膜病等，熟悉冠心病PCI术、心律失常射频消融术、起搏器植入等技术及其并发症的防治，主攻方向为冠心病的介入诊疗。参与《内科学》、《诊断学》的本科生及留学生等的见习、实习和授课工作。
I have engaged in internal medicine for more than 20 years and familiar with diagnosis and treatment of acute, sinister and serious symptoms in internal medicine, especially in acute heart failure, acute myocardial infarction, hypertensive crisis, aortic dissection and malignant arrhythmia. I am also skilled in diagnosis and treatment of cardiovascular’s common diseases, including of hypertension,coronary heart disease, cardiac arrhythmia, pericarditis, myocarditis, valvular heart disease, cardiomyopathy,etc. I am still good at techniques of percutaneous coronary intervention (PCI), arrhythmia radiofrequency ablation, pacemaker implantation and preventing complications of them. I am major in interventional therapy of coronary heart disease. Besides, I am enjoying in undergraduates and International Students’ probation, practice and teaching in internal medicine and diagnostics.
科研工作业绩（Scientific research performance）
心脏存在许多内源性的保护因子，互相联系形成网络，而单个因子的保护作用往往有限。不良刺激下心肌受到损伤时，这些因子互相调节发挥保护作用，但不良刺激因素长期存在时则打破了这种互相联系互相调节的网络关系，使得保护作用失效。早期激发心肌内源性保护机制是预防心力衰竭的关键问题之一，但干预单个因子保护心脏的作用有限，阐明多个因子的调节关系，从多个环节激发心肌的内源性保护机制是更有效的预防心脏疾病策略。本人长期致力于非编码RNA保护心脏疾病的研究。曾参与国家“863”项目﹑国家杰出青年科学基金﹑国家自然科学基金﹑复旦大学博士点基金等科研项目10余项，发表相关文章30余篇，其中20篇被SCI收录，作为负责人主持科研项目11项。
There are many endogenous protective factors in the heart and they contact each other forming a network. However, every single factor has own limitation in protecting heart. These factors regulate each other to protect the myocardium when it is damaged by harmful simulation, but the relationship between every factor can be broken by the long-term harmful simulation, which make the failures of protection. Simulating myocardial endogenesis protect mechanism is one of the key issues to protect heart failure. Nevertheless, the intervention of single factor is limited. So explaining the relationship between every factor and the simulating myocardial endogenesis protect mechanism in multiple ways are more effective in protecting heart disease. I work on the research of noncoding RNAs for a long time. I used to participate in more than ten scientific research programs and take charge of five of them, such as 863 Program, the National Natural Science Foundation of China, the National Science Fund for Distinguished Yonng Scholars, etc.. I have published more than thirty papers and twenty of them had been recorded by SCI.
近三年在研课题
Researching Programs recently 3 years
1.国家自然科学基金面上项目
General Program of National Natural Science Foundation of China
LincRNA01714上调S100A8介导中性粒细胞凋亡改善小鼠心力衰竭发生的机制研究
Study on mechanism of alleviating mouse heart failure through neutrophil apoptosis induced by up-regulating S100A8 via LincRNA01714
2.国家自然科学基金面上项目
General Program of National Natural Science Foundation of China
HFR-circRNA靶向miR-199b-5p/HSF1信号轴调控心力衰竭发生的机制研究
Mechanism study of HFR-circRNA targeting miR-199b-5p/HSF1 signal axis in the development of heart failure
3.国家自然科学基金面上项目
General Program of National Natural Science Foundation of China
《miR-199b-5p通过 HSF1信号途径调控心力衰竭发生的分子机制研究》
《Study on molecular mechanism of miR-199b-5p on heart failure mediated by HSF1 signal pathway》
4.浦东新区卫生和计划生育委员会学科带头人培养项目
Pudong New Area discipline leader training project
《circRNA-006964调控HSF1信号轴改善心力衰竭发生的作用及机制》
Experimental study of circRNA-006964 regulating HSF1 signal axis in the development of heart failure
