威尼斯(5848vip-WNS认证)电子游戏-Venice Dream City

脑血管病的临床、基础和器械研发

1、5848vip威尼斯电子游戏附属东方医院神经外科副主任 Deputy Director of Neurosurgery, Shanghai East Hospital, School of Medicine, Tongji University

2、5848vip威尼斯电子游戏附属东方医院南院神经外科执行主任 Executive Director of Neurosurgery, Shanghai East Hospital (South), School of Medicine, Tongji University

3、东方医院国家神经介入建设中心负责人 Director of National Neurointerventional Construction Center of Shanghai East Hospital

4、OCIN CASES执行主编 OCIN CASES Executive Editor

5、上海市神经介入医师专委会委员 Member of Shanghai Neurointerventional Physician Special Committee

擅长各种脑血管病的血管治疗，颅内外动脉瘤、夹层动脉瘤、椎基底动脉延长扩张症、脑血管畸形、颈动脉海绵窦瘘、硬脑膜动静脉瘘、颅内外血管狭窄、颅内静脉和静脉窦血栓、烟雾病、急性脑血管卒中、蛛网膜下腔出血、脑梗塞、颅内外血管慢性闭塞（开通术）等各种复杂脑血管病的治疗。主持/参与各项基金项目12项，参编脑血管病专著5部，以第一/共同第一作者在JNIS（IF=8.572）等SCI杂志发表论文14篇，其中单篇最高引用61余次。

I am skilled in the endovascular treatment of various cerebrovascular diseases, such as intracranial aneurysms, dissecting aneurysms, vertebrobasilar dilation, cerebrovascular malformations, carotid cavernous sinus fistulas, dural arteriovenous fistulas, intracranial and extracranial vascular stenosis, intracranial veins and venous sinuses thrombosis, moyamoya disease, acute cerebrovascular stroke, subarachnoid hemorrhage, cerebral infarction, chronic occlusion of intracranial and extracranial blood vessels, and so on. Presided over/participated in 12 funded projects. In addition, I have participated in compiling 5 books on cerebrovascular disease and published 14 papers in SCI journals, such as JNIS (IF=8.572), as the first/co-first author, of which a single paper has been cited more than 61 times.

一、代表性SCI论文

1. Zhao K, Zhao R, Yang X, et al. Predictors of unfavorable outcomes in the stent-assisted coiling for un-ruptured intracranial spontaneous vertebral artery dissections (uis-VADs): results from the multicenter study. J Neurointerv Surg, neurintsurg-2021-017619. doi:10.1136/neurintsurg-2021-017619

2. Zhao WY, Zhao KJ（共同第一）, Huang QH, Xu Y, Hong B, Liu JM. Single-stage endovascular treatment of subarachnoid hemorrhage related to bilateral vertebral artery dissecting aneurysms[J]. Interventional neuroradiology: journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences,2016, 22 (2): 138-142.

3. Yang P, Zhao K, Zhou Y, et al. Stent-assisted Coil Placement for the Treatment of 211 Acutely Ruptured Wide-necked Intracranial Aneurysms: A Single-Center 11-Year Experience. Radiology. 2015 Aug;276(2):545-52

4. Fang YB, Zhao KJ （共同第一）, Wu YN, et. al. Treatment of ruptured vertebral artery dissecting aneurysms distal to the posterior inferior cerebellar artery: stenting or trapping?. Cardiovasc Intervent Radiol. 2015 Jun;38(3):592-9.

5. Zhao KJ, Zhao R, Huang QH, et al. The interaction between stent(s) implantation, PICA involvement, and immediate occlusion degree affect symptomatic intracranial spontaneous vertebral artery dissection aneurysm (sis-VADA) recurrence after reconstructive treatment with stent(s)-assisted coiling. Eur Radiol. Sep 2014;24(9):2088-2096.

6. Zhao KJ, Zhang YW, Xu Y, et al. Reconstruction of saccular and dissected intracranial aneurysms using Solitaire AB stents. PLOS One. 2013;8(2):e57253.

7. Zhao KJ, Fang YB, Huang QH, et al. Reconstructive Treatment of Ruptured Intracranial Spontaneous Vertebral Artery Dissection Aneurysms: Long-Term Results and Predictors of Unfavorable Outcomes. PLOS One. 2013;8(6): e67169.

8. Yan J, Zhao K（共同第一）, Sun J, et al. Comparison between the formula 1/2ABC and 2/3Sh in intracerebral parenchyma hemorrhage. Neurological research. May 2013;35(4):382-388.

9. Zhang HF, Zhao KJ （共同第一）, Xu Y, et al. Lysyl oxidase polymorphisms and ischemic stroke--a case control study. Mol Biol Rep. Oct 2012;39(10):9391-9397.

10. Xu YZ, Zhao KJ （共同第一）, Yang ZG, et al. Decreased plasma decorin levels following acute ischemic stroke: correlation with MMP-2 and differential expression in TOAST subtypes. Mol Med Rep. Dec 2012;6(6):1319-1324.

11. Zhao KJ, Yang PF, Huang QH, et al. Y-configuration stent placement (crossing an kissing) for endovascular treatment of wide-neck cerebral aneurysms located at 4 different bifurcation sites. AJNR. American journal of neuroradiology. Aug 2012;33(7):1310-1316.

12. Zhang HF, Zhao KJ (共同第一), Yang PF, et al. Association between fibroblast growth factor receptor 4 Gly388Arg polymorphism and ischemic stroke. J Int Med Res. 2012;40(5):1708-1714.

13. Zhao KJ, Zhang RY, Sun QF, et al. Comparisons of 2/3Sh estimation technique to computer-assisted planimetric analysis in epidural, subdural and intracerebral hematomas. Neurological research. Nov 2010;32(9):910-917.

14. Zhao KJ, Liu Y, Zhang RY, Wang XQ, Gao C, Shen JK. A precise, simple, convenient and new method for estimation of intracranial hematoma volume--the formula 2/3Sh. Neurological research. Dec 2009;31(10):1031-1036.

15. Zhang RY, Zhao KJ, Tang YQ, Li L. Effect of isoflavone extracts from glycine max on human endothelial cell damage and on nitric oxide production. Menopause.2010;17:441-442.

16. Zhang RY, Cui W, Zhao KJ, et al. Validating sampling methods for measurement of circulating matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1. Pancreas, 2010;39(6):937-938.

二、代表性中文论文

1. 赵开军,王杰军,方亦斌,李佑祥,黄清海,赵瑞,杨新健,刘建民.支架重建技术治疗未破裂颅内自发性椎动脉夹层动脉瘤的预后及其影响因素[J].中华神经外科杂志,2018,34(8): 773-777.

2. 赵开军，杨鹏飞，黄清海等.Y型支架技术治疗颅内动脉分叉部宽颈动脉瘤[J].中国临床神经外科杂志.2013.18（6）：321-324.

3. 赵开军,沈建康. 颅内血肿体积评估方法的影像和临床进展[J],中华神经外科疾病研究杂志,2010,9: 376-378.

4. 赵开军, 沈建康. 颅内血肿体积评估方法的影像和临床进展[J]. 中华神经外科疾病研究杂志, 2010, 9 : 376-378.

5. 赵开军, 沈建康. 胃泌素释放肽受体在肿瘤治疗中的研究进展[J]. 世界华人消化杂志, 2009, 17 (1): 63-67.

6. 赵开军,沈建康,孙青芳.胃泌素释放肽受体在肿瘤中分布的临床意义[J]. 国际肿瘤学杂志, 2008, 35 (9)

7. 赵开军, 任光阳. 极限法在颅内血肿体积计算中的应用[J]. 中华神经外科杂志, 2007, 23 (005): 363-363.

8. 赵开军, 任光阳. Chiari 畸形脊髓空洞症发病机制的力学探讨[J]. 中华神经外科杂志, 2006, 22: 642-644.

三、现阶段主持中的课题（在研科研经费：70万）

1.北京医学奖励基金会，神经科学创新发展研究项目，YXJL-2022-00351-0183，远桡或传统桡动脉入路诊疗症状性脑血管病致围手术期桡动脉闭塞的风险分析：一项前瞻性、单中心、随机、对照研究，2022.08.01-2025.08.01，在研，主持，30万；

2、上海市东方医院，引进人才启动基金，30万；

3.军队，“234学科攀峰计划”，2019YXK030,未破裂的椎基底动脉夹层（VBD）重建性治疗大数据分析及前瞻性研究，2020-01至2023-12，在研，主持，10万；

4.军队，长海医院教学研究与改革项目，CHJG2019036,借助3D图像和视频巧学动脉瘤微导管的塑形技术，2020-01至2020-12，在研，主持。

	赵开军副主任医师
	硕士招生类型：专业型硕士招生专业：神经外科博士招生类型：博士招生专业：
	所在院系：附属东方医院
	联系方式：zkjwcfzwh@163.com
	课题组链接：

研究方向主要任职科研业绩脑血管病的临床、基础和器械研发 1、5848vip威尼斯电子游戏附属东方医院神经外科副主任 Deputy Director of Neurosurgery, Shanghai East Hospital, School of Medicine, Tongji University 2、5848vip威尼斯电子游戏附属东方医院南院神经外科执行主任 Executive Director of Neurosurgery, Shanghai East Hospital (South), School of Medicine, Tongji University 3、东方医院国家神经介入建设中心负责人 Director of National Neurointerventional Construction Center of Shanghai East Hospital 4、OCIN CASES执行主编 OCIN CASES Executive Editor 5、上海市神经介入医师专委会委员 Member of Shanghai Neurointerventional Physician Special Committee 擅长各种脑血管病的血管治疗，颅内外动脉瘤、夹层动脉瘤、椎基底动脉延长扩张症、脑血管畸形、颈动脉海绵窦瘘、硬脑膜动静脉瘘、颅内外血管狭窄、颅内静脉和静脉窦血栓、烟雾病、急性脑血管卒中、蛛网膜下腔出血、脑梗塞、颅内外血管慢性闭塞（开通术）等各种复杂脑血管病的治疗。主持/参与各项基金项目12项，参编脑血管病专著5部，以第一/共同第一作者在JNIS（IF=8.572）等SCI杂志发表论文14篇，其中单篇最高引用61余次。 I am skilled in the endovascular treatment of various cerebrovascular diseases, such as intracranial aneurysms, dissecting aneurysms, vertebrobasilar dilation, cerebrovascular malformations, carotid cavernous sinus fistulas, dural arteriovenous fistulas, intracranial and extracranial vascular stenosis, intracranial veins and venous sinuses thrombosis, moyamoya disease, acute cerebrovascular stroke, subarachnoid hemorrhage, cerebral infarction, chronic occlusion of intracranial and extracranial blood vessels, and so on. Presided over/participated in 12 funded projects. In addition, I have participated in compiling 5 books on cerebrovascular disease and published 14 papers in SCI journals, such as JNIS (IF=8.572), as the first/co-first author, of which a single paper has been cited more than 61 times. 一、代表性SCI论文 1. Zhao K, Zhao R, Yang X, et al. Predictors of unfavorable outcomes in the stent-assisted coiling for un-ruptured intracranial spontaneous vertebral artery dissections (uis-VADs): results from the multicenter study. J Neurointerv Surg, neurintsurg-2021-017619. doi:10.1136/neurintsurg-2021-017619 2. Zhao WY, Zhao KJ（共同第一）, Huang QH, Xu Y, Hong B, Liu JM. Single-stage endovascular treatment of subarachnoid hemorrhage related to bilateral vertebral artery dissecting aneurysms[J]. Interventional neuroradiology: journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences,2016, 22 (2): 138-142. 3. Yang P, Zhao K, Zhou Y, et al. Stent-assisted Coil Placement for the Treatment of 211 Acutely Ruptured Wide-necked Intracranial Aneurysms: A Single-Center 11-Year Experience. Radiology. 2015 Aug;276(2):545-52 4. Fang YB, Zhao KJ （共同第一）, Wu YN, et. al. Treatment of ruptured vertebral artery dissecting aneurysms distal to the posterior inferior cerebellar artery: stenting or trapping?. Cardiovasc Intervent Radiol. 2015 Jun;38(3):592-9. 5. Zhao KJ, Zhao R, Huang QH, et al. The interaction between stent(s) implantation, PICA involvement, and immediate occlusion degree affect symptomatic intracranial spontaneous vertebral artery dissection aneurysm (sis-VADA) recurrence after reconstructive treatment with stent(s)-assisted coiling. Eur Radiol. Sep 2014;24(9):2088-2096. 6. Zhao KJ, Zhang YW, Xu Y, et al. Reconstruction of saccular and dissected intracranial aneurysms using Solitaire AB stents. PLOS One. 2013;8(2):e57253. 7. Zhao KJ, Fang YB, Huang QH, et al. Reconstructive Treatment of Ruptured Intracranial Spontaneous Vertebral Artery Dissection Aneurysms: Long-Term Results and Predictors of Unfavorable Outcomes. PLOS One. 2013;8(6): e67169. 8. Yan J, Zhao K（共同第一）, Sun J, et al. Comparison between the formula 1/2ABC and 2/3Sh in intracerebral parenchyma hemorrhage. Neurological research. May 2013;35(4):382-388. 9. Zhang HF, Zhao KJ （共同第一）, Xu Y, et al. Lysyl oxidase polymorphisms and ischemic stroke--a case control study. Mol Biol Rep. Oct 2012;39(10):9391-9397. 10. Xu YZ, Zhao KJ （共同第一）, Yang ZG, et al. Decreased plasma decorin levels following acute ischemic stroke: correlation with MMP-2 and differential expression in TOAST subtypes. Mol Med Rep. Dec 2012;6(6):1319-1324. 11. Zhao KJ, Yang PF, Huang QH, et al. Y-configuration stent placement (crossing an kissing) for endovascular treatment of wide-neck cerebral aneurysms located at 4 different bifurcation sites. AJNR. American journal of neuroradiology. Aug 2012;33(7):1310-1316. 12. Zhang HF, Zhao KJ (共同第一), Yang PF, et al. Association between fibroblast growth factor receptor 4 Gly388Arg polymorphism and ischemic stroke. J Int Med Res. 2012;40(5):1708-1714. 13. Zhao KJ, Zhang RY, Sun QF, et al. Comparisons of 2/3Sh estimation technique to computer-assisted planimetric analysis in epidural, subdural and intracerebral hematomas. Neurological research. Nov 2010;32(9):910-917. 14. Zhao KJ, Liu Y, Zhang RY, Wang XQ, Gao C, Shen JK. A precise, simple, convenient and new method for estimation of intracranial hematoma volume--the formula 2/3Sh. Neurological research. Dec 2009;31(10):1031-1036. 15. Zhang RY, Zhao KJ, Tang YQ, Li L. Effect of isoflavone extracts from glycine max on human endothelial cell damage and on nitric oxide production. Menopause.2010;17:441-442. 16. Zhang RY, Cui W, Zhao KJ, et al. Validating sampling methods for measurement of circulating matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1. Pancreas, 2010;39(6):937-938. 二、代表性中文论文 1. 赵开军,王杰军,方亦斌,李佑祥,黄清海,赵瑞,杨新健,刘建民.支架重建技术治疗未破裂颅内自发性椎动脉夹层动脉瘤的预后及其影响因素[J].中华神经外科杂志,2018,34(8): 773-777. 2. 赵开军，杨鹏飞，黄清海等.Y型支架技术治疗颅内动脉分叉部宽颈动脉瘤[J].中国临床神经外科杂志.2013.18（6）：321-324. 3. 赵开军,沈建康. 颅内血肿体积评估方法的影像和临床进展[J],中华神经外科疾病研究杂志,2010,9: 376-378. 4. 赵开军, 沈建康. 颅内血肿体积评估方法的影像和临床进展[J]. 中华神经外科疾病研究杂志, 2010, 9 : 376-378. 5. 赵开军, 沈建康. 胃泌素释放肽受体在肿瘤治疗中的研究进展[J]. 世界华人消化杂志, 2009, 17 (1): 63-67. 6. 赵开军,沈建康,孙青芳.胃泌素释放肽受体在肿瘤中分布的临床意义[J]. 国际肿瘤学杂志, 2008, 35 (9) 7. 赵开军, 任光阳. 极限法在颅内血肿体积计算中的应用[J]. 中华神经外科杂志, 2007, 23 (005): 363-363. 8. 赵开军, 任光阳. Chiari 畸形脊髓空洞症发病机制的力学探讨[J]. 中华神经外科杂志, 2006, 22: 642-644. 三、现阶段主持中的课题（在研科研经费：70万） 1.北京医学奖励基金会，神经科学创新发展研究项目，YXJL-2022-00351-0183，远桡或传统桡动脉入路诊疗症状性脑血管病致围手术期桡动脉闭塞的风险分析：一项前瞻性、单中心、随机、对照研究，2022.08.01-2025.08.01，在研，主持，30万； 2、上海市东方医院，引进人才启动基金，30万； 3.军队，“234学科攀峰计划”，2019YXK030,未破裂的椎基底动脉夹层（VBD）重建性治疗大数据分析及前瞻性研究，2020-01至2023-12，在研，主持，10万； 4.军队，长海医院教学研究与改革项目，CHJG2019036,借助3D图像和视频巧学动脉瘤微导管的塑形技术，2020-01至2020-12，在研，主持。